PRL-8-53 is a cognitive enhancement research chemical derived from benzoic acid and phenylmethylamine. It has reported research of amazing memory enhancement, where volunteers almost doubled their ability in recalling words however the research on this molecule was abandoned for reasons unknown.

It is purchasable on the internet, but because of the novel nature of this drug, it is unclear whether anyone really ever tried the real thing, or if it even works.

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PRL 8 53 Experiences - Supplements - LONGECITY

Page 1 of 2 - PRL 8 53 Experiences - posted in Supplements: I created this topic for PRL-8-53 because I didn't find an appropriate listing in the forum and I am personally very intrigued by the results claimed by wikipedia in some studies with this substance."Subjects were given 12-item word lists to memorize as part of the trial. While initial word acquisition performance on PRL-8-53 was only 107.46% of baseline, subjects recalled words at 132.5-142.7% of the baseline rate 24 hour...

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“Back in 1978...one study is hardly enough, but lots of anecdotal evidence of it working though...Semax still seems better.

PRL-8-53: enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent.

The effect of 3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride (PRL-8-53) on learning and on retention of verbal information in human subjects was investigated. Using the serial anticipation method under double-blind conditions it was found that PRL-8-53 causes slight improvement of acquisition. Retinetion of verbal information was found improved to a statistically significant degree (most P values better than 0.01, some better than 0.001). No significant changes were found for either visual reaction time or motor control after drug when compared with placebo values.

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